Tissue stretch induces nuclear remodeling in connective tissue fibroblasts
نویسندگان
چکیده
منابع مشابه
inductive effect of palatal connective tissue on alveolar mocosa after subepithelial connective tissue graft clinical & histologic study
چکیده ندارد.
15 صفحه اولConnective tissue fibroblasts and Tcf4 regulate myogenesis.
Muscle and its connective tissue are intimately linked in the embryo and in the adult, suggesting that interactions between these tissues are crucial for their development. However, the study of muscle connective tissue has been hindered by the lack of molecular markers and genetic reagents to label connective tissue fibroblasts. Here, we show that the transcription factor Tcf4 (transcription f...
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Although the etiology of varicose veins remains unknown, recent studies have focused on endothelial cell integrity and function because the endothelium regulates vessel tone and synthesizes many pro- and anti-inflammatory factors. The aim of this study was to investigate the evidence involving the endothelium in the development of varicose vein disease. In addition, tissue remodeling was invest...
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Matrix metalloproteinases are an important group of zinc enzymes responsible for degradation of the extracellular matrix components such as collagen and proteoglycans in normal embryogenesis and remodeling and in many disease processes such as arthritis, cancer, periodontitis, and osteoporosis. A matrixin family is defined, comprising at least seven members that range in size from Mr 28,000 to ...
متن کاملA connective tissue growth factor signaling receptor in corneal fibroblasts.
PURPOSE To biochemically characterize the receptor for connective tissue growth factor (CTGF) of human corneal fibroblasts (HCF). METHODS Radiolabeled recombinant human CTGF was used to determine the specificity and time course of binding to low-passage cultures of HCF. The affinity and number of receptors present were calculated by Scatchard and best-fit analyses. In vitro immunoprecipitatio...
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ژورنال
عنوان ژورنال: Histochemistry and Cell Biology
سال: 2010
ISSN: 0948-6143,1432-119X
DOI: 10.1007/s00418-010-0680-3